Abstract
There have been published many researches about water in the various fields such as agriculture, chemistry, biology, medicine and physics. The targets of water research are these in daily life, ocean and in the air besides in the substances. Moreover, there are the theoretical study of water (H₂O) itself. Ab initio calculation and the density-functional theory have been reported on the hydrogen bond of water molecules and interaction between monomers, which research issue is associates with the water molecule itself. Here we present the theoretical concept to protect any virus involving in COVID-19, and the mechanism based on the reaction of amino acids with water involving a proton and electron which are essential to our body. It has been performed with the dissociation of hydrogen bond due to pressurization (more than 200 MPa) applied to ordinary water. Besides the smallness, the proton and electron may play a role to pass an electric current to protect a virus and a germ through the water in the body. The information of the water is supposed to be “momentum” (spin, mass and velocity) may protect any virus and germ due to chemical reduction by proton and electron in the water.

Keywords: Weak energy water; Proton & electron; Hydrogen bond; COVID-19, Amino acid

Abstract
According to tremendous translational researchers, biomarkers as a part of the ligand-receptor tandems have induced an impulse to prompt the evolution of an upgraded concept of the targeted therapy. It is health indicators that justifying the necessity to create targeted drug of the next-step generation to be implemented at the clinical and sub-clinical key stages of the disease process and to get involved into a multi-stage process to get the shifts appeared modified.

There is an evident-based outcome of the latest studies in multiple sclerosis (MS) related fields that illustrates the proved targeted activity of Ab-proteases. High impact of Ab-proteases can be used to monitor both clinical and subclinical courses of chronic autoimmune inflammation (MS) to predict stepwise transformations of the course and to prognosticate the clinical illness  finally. In this sense, Ab-proteases can be programmed and reprogrammed to suit the requests and standards of regenerative medicine and re-myelination, in particular. This data makes it possible to design the algorithms for combinatorial (preventive, prophylactic, therapeutic and rehabilitative) treatment, whilst developing unique tools for individually therapy, especially, for autoimmune diseases which holds a particular position.

Abstract
One way to store electrical energy takes place by electrolysis of alkaline water, hydrogen and oxygen obtained are stored and thereafter be re-used as fuels in internal combustion engines or in fuel cells which are cheaper, safer than the latter. Among these fuel cells, CFLs we find English Alkaline Fuel Cell. The electrolyte of the fuel cell is a potassium hydroxide solution, the chemical reaction that occurs within the fuel cell is the recombination of hydrogen with oxygen to give water, electric energy and heat energy.

One of the major challenges for the proper functioning of the fuel cell is discharging water and heat that can damage the electrolytic solution; therefore, it is essential to master the phenomena of mass transfer of water that operates within the fuel cell, and the optimum temperature of the inlet gas, knowing that fuel cells typically operate in isothermal conditions. This mastery must first go through the modeling of these phenomena then the real-time simulation of the main factors involved ensuring good cell efficacy. This model is articulated around Nernst-Planck equations, the equation of continuity and the two of Fick laws. The resolution of these equations requires a numerical approach of the partial differential equations.

Keywords: Water transport; AFC Alkaline Fuel Cell; Hydrogen; Oxygen; Mathematical Model

Abstract
At present the interest inidentify and satisfy consumer needs for this companies use various techniques such as the study of market, conducting surveys, product testing by mention a few, nowadays to get a better result precise techniques and tools have evolved a lot. Neuromarketing is one of those advances, which helps us to determine with greater accuracy and depth the preferences of the consumer. Focus on knowing conscious behavior, while the consumer buying behavior is fundamentally  unconscious. Today with the help of new technologies more interest has developed in applying the methods of neurology in various areas other than medicine, that are related to human behavior, being the Neuromarketing one of the ways to investigate and know consumer behavior and decision-making purchase, thus supporting us to better understand the psychological behavior and dictate more precise actions to marketing based on the knowledge of the reactions cerebral.

Keyword: Neuromarketing; Emotion; Neuroscience; Neuron; Neural network

Abstract
Plant Nutrient Role and Requirement: Plants like other organisms require “FOOD” for their living and growth development. From chemical elements drawn from soil, water, and air, plants build a vast array of plant products.
Plan for Agricultural Water Management: Alleviation and reduction of poverty amongst people in mainly rural areas, and rehabilitation, protection and reclamation of water works and water resources.
Materials and Methods: Cow peas (Vigna Unguiculata), (Vigna subterranean – bambara groundnut, Groundnuts (Arachis hypogaea L.), Black gram (Vigna mungo (L.) Hepper) and Mungbeans (Vigna radiate (L.) Wilzcek). Field trial lay out plan (Randomized Complete Block Design), plant sampling and processing (10 plants per plot size), measurement of ¹³C/¹²C isotopic ratio (Lab instrument; Spectrometry) and statistical analysis Statistica 10.1 (StatSoftInc., Tulsa, OK, USA).
Results: Although there are several reports on symbiotic (N) performance of cowpea, Bambara groundnut, groundnut and mungbean, studies on their C accumulation, shoot C/N ratio, and shoot-water-use efficiency are few. Therefore, evaluation of these parameters in the test grain legumes widely cultivated in South African smallholder sector it was an objectives of the current study where groundnut exhibited high WUE compared to the other grain legumes planted for testing.
Discussion: The aim of this study was therefore to determine the C accumulation and WUE of five grain legumes using C isotopic discrimination (¹³C/¹²C) values during the 2011/2012 cropping season. South Africa is a semi-arid country with an annual average rainfall < 500 mm in two-thirds of its land mass.
Conclusion: Shoot-biomass (g.plant^-1) was high to Bambara-groundnut, C concentration (%) was also high to both Bambara- groundnut and groundnut, C content (g.plant_^-1) was higher to Bambara-groundnut, Σ¹³C (‰) was high to groundnut and Bambara-groundnut while the C:N ratio of mung-bean was highest in the study. Therefore WUE reveal that groundnut and Bambara-groundnut are the best users of water whereas other legumes utilize water inefficient compared to the two legumes.

Volume 1 , Issue 5

 Editorial

Sustainable Manufacturing: A Step for Mindful Consumption and Circular Economy

N Gupta

Published: November 11, 2021.

PDFAbstract

 Review Article

Deep LSTM-based Automated Learning Environment using Smart Data to Improve Awareness and Education in Time Series Forecasting

Zair Bouzidi, Abdelmalek Boudries and Mourad Amad

Published: November 11, 2021.

PDFAbstract

 Review Article

Review on Pharmacological and Therapeutic Potential of Cuscuta species

Narmatha G, Sandhiya S, Kokila J, Poovizhi T and Savitha T

Published: November 19, 2021

PDFAbstract

 Research Article

Evaluation of Impact of SARS COVID-19 Virus on Sexual Assault Cases in India

Yogesh Yadav, Gosia Khan and Garima Chaudhary

Published: November 26, 2021

PDFAbstract

 Research Article

The Water Protects a Virus with the Weak Energy Involving the Elementary Particles

Sunao Sugihara and Yuji Nagasaka

Published: November 30, 2021

PDFAbstract

 Review Article

A New Generation of Translational Tools designed to Monitor Multiple Sclerosis (MS) at Clinical and Subclinical Stages

Mariya Studneva, Noel Rose, Aleks Gabibov, Veronika Medvedeva, R. Holland Cheng and Sergey Suchkov

Published: November 30, 2021

PDFAbstract

 Letter to Editor

The Legend of Dr. Kotnis: An Inspiration for Global Healthcare Cooperation.

Sameer S Deshmukh

Published: November 30, 2021

PDFAbstract

 Opinion

Homeopathy - Myths and Facts about Gastric Issues

Yatri Thacker

Published: November 30, 2021

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 Short Communication

Bullying, a Major Contributor to Cultism

Adesanya Omowumi

Published: November 30, 2021

PDFAbstract

 Review Article

COVID-19 Pandemic: Upswing in Antibiotic Misuse

Novy Gupte

Published: November 30, 2021

PDFAbstract

Abstract
The ongoing COVID-19, caused by the new coronavirus, SARS-CoV-2, after originating from the Wuhan City of China, was declared a “pandemic” on 11 March 2020 by the World Health Organization (WHO). Availability of a number of vaccines against COVID-19 may prove a game-changer. However, in the absence of an acceptable specific antiviral agent, therapeutic approaches in an overwhelming majority of the cases are a cocktail of symptomatic/supportive measures, immunity boosters, immunomodulators, immunotherapy, steroids and antimicrobials. In life-threatening situations in hospitalized patients, critical care measures are adopted. In deference to the recommendations of the WHO, antibiotics such as azithromycin and doxycycline continue to be consumed irrationally in a large proportion of the patients even in absence of a bacterial coinfection, especially in the resource-limited countries. The widespread misuse of antibiotics is likely to have worsened the already existing problem of antimicrobial resistance (AMR). The endeavors aimed at controlling the COVID-19 pandemic (that has been causing huge morbidity and mortality worldwide and adversely impacting economy), need to be complemented with spirited and restrengthened campaign against irrational antibiotic use that is augmenting the AMR. Also, there is a need for promoting antibiotic prudency through alternative and complementary therapies. Most importantly, developing the new antibiotics from new classes should be a top priority.

Keywords: Antibiotic prudency; Antimicrobial resistance; Multidrug resistance; New antibiotics; Superbugs

Abstract
Rice cultivation is one of the important economic activities of farmers, and it has been the backbone of livelihood opportunities for several farmers in certain areas. However, due to the limited availability of freshwater and the progressive decline in the share of water for agriculture (because of water pollution, reducing water table, inefficient irrigation systems, and increasing demands of water for domestic, industrial and other usages) cultivation of rice by transplanting cannot be sustained. The water-guzzling nature of transplanted rice (TPR) is facing the challenges of water scarcity, posing threats to continued rice cultivation. Moreover, repeated puddling for TPR adversely affects soil physical properties, deteriorates the performance of succeeding crops, and contributes to methane gas emissions. A grim water scenario in agriculture together with the highly inefficient rice production technologies, currently adopted by a majority of farmers globally, warrants the exploration of alternative rice production practices. Therefore, the need of the day is to use less water for irrigation while maintaining the crop yield (as well as the quality of the produce) for better water-productivity towards the concept of ‘Per Drop More Crop’. Direct-sown rice (DSR) is an emerging resource-conserving, climate-smart alternative to TPR. DSR is gaining popularity because of its low input cost and resource-conserving nature. It offers the advantages like saving irrigation water, lower labor requirements, less drudgery, early crop maturity, higher economic returns, and reduced methane emission. The need of conserving natural resources, particularly water, for better ecological balance has become one of the priorities for saving life on the earth. Producing food/feed/fodder in an environment-friendly manner by adopting agricultural practices that do not over-exploit the natural resources and harm agroecological conditions is necessary for maximum ecological efficiency.

Abstract 
Children are the gift given by God to humanity. Sexual abuse of Children is one of the most heinous crimes. CSA (child sexual abuse) and SA (Sexual Assault) is the most reported crime against children across worldwide. It affects not only physically but also mentally it may lead to death. Both girls and boys in India face severely assault like early marriage, domestic violence, bullying, child labor, and many more children can be sexually assaulted in any place like home, streets, schools, workplaces, prisons, orphans. It affects the overall development of the children. According to NCRB 109 children face any form of CSA every day in India. Keeping in view the alarming situation of sexual crime against children. Indian government passed a law against the crime against women in 2018 and the crime against children in 2012. In 2012, the amendment of the POCSO (Protection of children from sexual offenses) act in sections 4, 5, 6, 9, 14, 15 and 42 is made to save the children from sexual assaults. 

     The objective of our study is to describe the overall crime rate of DELHI NCR on child abuse and sexual assaults in the year 2019, March 2019 to June 2021, under IPC 376, 377, 354, POCSO Act 2012, etc. Forensic Laboratory receives 5-10 cases of child sexual abuse every month. In most cases, the criminal is known and/or unknown to the victim. In this study, we also try to create awareness towards the Sexual Assault and the POCSO Act.

Abstract
The plant genus Cuscuta, belongs to the family Cuscutaceae, has been traditionally used as therapeutic treasure against various metabolic and neurological diseases such as mental abstraction, headache, spleen disease, jaundice, diabetes mellitus and hypertension. There are numerous secondary metabolites have been identified that are considered as phytochemical constituents, such as alkaloids, flavonoids, lignins, steroids, phenolic acids, fatty acids, glycosides and polysaccharides. Due to the presence of these bioactive ingredients, various ethnopharmacological actions including anticancer, antiviral, antisapasmodic, antihypertensive, antibacterial, antioxidant, diuretic, antihypertensive were explored. This review brings eyesight for the explorations of novel therapeutic agents for the various ailments of mankind. 
Keywords: Therapeutic treasure; Phytoconstituents; Pharmacological activity

Abstract
Many theoretical water reports have been often published; moreover, development and or applications spread in various fields. Even the limited area, academic discussions increased since the late 1970s, although they were not necessarily relating to water itself. Ab initio calculation and the density-functional theory have been reported on the hydrogen bond of water molecules and interaction between monomers since the 21^st century. Every research issue is associates with the water molecule itself. Here we present the theoretical idea to protect COVID-19 and the mechanism based on the water with a pico-sized particle, which is essential to our body. It has been performed with the dissociation of hydrogen bond due to pressurization (at 147 MPa) applied to normal water so that the body can quickly absorb the water. Besides the smallness, the characteristics of the water can transfer the information of the particle even in the area. The information is supposed to be “momentum” (mass and velocity) same as the solar beam emitting seven visible lights, and the data of the particle might be printed in the other matter which nature can transmute. However, we cannot visualize the information of the particle such as solar beam at present.

Abstract
Urea application is a fundamental practice to increase rice grain yields, but it also plays a significant role in CH₄ emission from rice paddy fields. To quantify the effect on CH₄ emission, we measured soil dissolved organic carbon (DOC) content, CH₄ production potentials of paddy soil and rice roots, CH₄ concentration in soil pore water, and their corresponding stable carbon isotopes (δ¹³C) under four urea application rates (0, 120, 240 and 300 kg N ha^-1) in 2010–2015 based on incubation, pot and field experiments. In addition, the abundance of methanogenic archaea in paddy soils was quantified by quantitative PCR targeting mcrA genes. Field and pot experiments show that urea addition decreased seasonal CH₄ emissions by 20–35% and enhanced δ¹³C-values of emitted CH₄ by 3‰ on average. The decreased CH₄ production potentials in paddy soil and on rice roots (by 16–30%) were found to be the major reason for the reduction of CH₄ emission with urea addition. In contrast, applying urea increased the content of soil DOC and the abundance of methanogenic mcrA genes. The contribution of acetoclastic methanogenesis was also increased by urea addition both in the soil (by 10–12%) and on the roots (by 5%), which might have positive effects on the δ¹³C-values of emitted CH₄ and porewater CH₄. The findings demonstrate that the decrease of CH₄ emission was attributed to CH₄ production reduced with urea addition, and the promotion of acetate-dependent methanogenesis was possibly ascribed to related methanogenic substrates and archaea increased.

Keywords: N addition; CH₄ production; Stable carbon isotopes; Methanogenic archaea; Methanogenic pathway; Rice-based cropping system

Abstract
This proposed commercial model is based on deep Long Short-Term Memory Network (LSTM), used because of its ability to learn long term dependencies, in taking the concatenated function and market data as input, while integrating Smart Data encapsulations, retrieving information by combining various search results (all the Web). It provides some good ideas for that we have extended to improve Corporate Marketing and Business Strategies. We show that the proposed model learns to both localize and recognize their different aspects. We evaluate it on the challenging task of detecting Fraud in Financial Services and Financial Time Series Forecasting and show that it is both more accurate than the state-of-the-art of other neural networks and uses fewer parameters and less computation.

Keywords: Awareness; Business; Education; LSTM; Smart Data

Abstract
This Paper provides an analysis of the Challenges and Opportunities for Technical Education, globally and with particular reference to India. The concept of Grand Challenges is first explained, followed by the Grand Challenges for Technical Education in India. The evolution of Engineering Education systems worldwide is traced through the response of Global and National Engineering Education to Industry 5.0. The impact of pervasive Change all around us is demonstrated through several examples, leading to the demise of business and education as usual. The special features of XXI Century Learners and Teachers, the emerging changes in employment and careers and the opportunities and challenges for Engineering Education in India are next discussed. Th evolution of Industry 1.0 to 5.0 is next traced along with the corresponding evolution of Education 1.0 to 5.0. The dire need for changes in Engineering Education Systems and Processes is demonstrated through the changes in the four subsystems comprising the overall system. The future of Engineering Education is postulated in terms of the integration of several features which have existed as separate entities till now, and the creation of Education 5.0 -compatible graduates.

Abstract
PRP, in any case called Platelet Rich Plasma, was expected to help men experiencing erectile dysfunction by improving sexual performance. The PRP Intimate shot is a non-surgical procedure for normal sexual upgrade clinically proven treatment option, with great many patients overall accomplishing improved sexual advantages. This procedure uses growth factors extricated from own sample blood, animating new tissue growth inside the penis. This process uses PRP, or Platelet Rich Plasma, a supplement and growth factors rich portion of own blood, making it protected and natural. The analysts presumed that PRP can possibly be a valuable treatment option for ED. PRP infusions for erectile dysfunction, now and again called the P shot, can help fortify erection. The P-Shot incorporates taking platelet-rich plasma (PRP) from your blood and imbuing it into penile tissue. This implies own cells and tissues and infuses them into penile tissues to promote tissue growth and purportedly give better erections. In any case, keep at the top of the priority list that the examinations had little sample sizes, and there weren’t satisfactory comparison groups. More exploration is expected to comprehend the advantages of PRP treatment. The current evidence is for the most part episodic.

Keywords: PRP Treatment; P-Shot Treatment; Erectile Dysfunction

Abstract
A total of two hundred and seventy (270) day old broiler chicks were used to evaluate the effect of feeding graded level of whole sugarcane waste with or without fishmeal and grasshopper meal supplementation in the diet of broiler. The diet formulated had three (3) inclusion levels of Whole sugarcane waste (WSW) at 0, 5, 10 %, with animal protein supplementation (fishmeal and grasshopper meal) at 2.5%. The experimental animals were randomly distributed into nine dietary treatments. There were three replicates per treatment with ten birds per replicates. Feed and water were supplied ad-libitum while standard poultry management where strictly followed during the study. Data on different performance parameters such as average daily feed intake, average daily weight gain, feed conversion efficiency and cost of feed where collected. It was a 3×3 factorial experiment in a complete randomized design (CRD). The experiment lasted for a period of (8) weeks. The result showed that the experimental diet had significant effects (P<0.05) on final weight, daily feed intake, weight gain and feed to gain ratio. Supplement interaction showed significant difference on final weight, daily feed intake, and feed to gain ratio. This study showed that broilers fed 5% Whole sugar cane waste supplemented with grasshopper meal had better performance as it gave better growth performance When compared to 10% inclusion level.

Abstract
A 67 kDa acid invertase (specific activity = 780 U/mg protein), appreciably present in Lagenaria siceraria stem (2,600 + 200 U /100 g fresh wt.; 17,500 + 300 U/100 g of lyophilized stem powder) was purified by (NH4)2SO4 precipitation, ion exchange chromatography (DEAE Sephadex A50), size exclusion chromatography (Sephacryl S-300-HR) and HPLC. The enzyme was optimally active in the pH range of 4-5 (retaining 52 + 1 % of its activity at pH 3) and stable in the pH range of 3-7 (retaining 37 + 1% and 53 + 1% of its activity at pH 2 and 8 respectively), up to 55°C, with a Km of 5.84 mM (2 mg/ml) sucrose. Hg2+> Ag+>Cu2+>Pb2+>Cd2+ inhibited the enzyme activity. DTNB, iodoacetic acid, iodoacetamide, N-ethylmaleimide did not affect the activity suggesting the non-thiol nature of the enzyme. The enzyme hydrolyzed sucrose and raffinose, could slightly hydrolyze inulin, but was completely inactive upon maltose, levan, melezitose and trehalose. 8 U/ml of acid invertase almost completely hydrolyzed 10% (w/v) sucrose solution to invert syrup in 5 h at 50°C. Immobilization of the enzyme on oxidized bagasse (dialdehyde cellulose) increased its temperature optima (by 10°C) and thermo-stability (retaining 41 + 1% and 30 + 1 % of its activity at 70°C and 80°C respectively). Immobilized enzyme system efficiently produced invert syrup from sucrose, remaining 83 + 1 % and 72 + 1 % active after 15th and 25th cycles respectively.

Keywords: Lagenaria siceraria; Acid invertase; Sucrose; Invert syrup; Cellulose-dialdehyde

The present crop production is heavily reliant on the sole use of chemical fertilizers in most sub-Saharan African countries e.g. in Malawi. In the very first years of practicing chemical fertilization, farm returns continued to rise as due to the responsiveness of the soils to chemical soil amendments. However, continued sole application of chemical fertilizers has led to negative impacts on soil health, crop productivity as well as on the environment. Synonymously, organic fertilization alone has proved to be futile on yield due to unbalanced nutrient content.

Abstract
This research work was undertaken to explore the neuroprotective potential of Sargassum wightii against scopolamine-induced dementia in rats. Progressive loss of memory is a most prominent symptom in neurodegenerative diseases. Five groups of animal were used for this experiment and scopolamine (16 mg/kg body weight/ i.p.) was administered to induced dementia like symptoms. Behavioral study was performed by Morris Water Maze test (MWM) to assess learning and memory, biochemical parameter such as acetylcholinesterase enzyme (AChE) activity was measured to analyze cholinergic activity in brain, the oxidative biomarker enzyme status was estimated by analysis of malondialdehyde (MDA), GSH and histopathological assessed were then performed. Scopolamine 16 mg/kg body weight significantly impaired acquisition and memory in Morris water maze test. Pretreatment with Sargassum wightii (methanolic extract) both the doses 200mg/kg and 400mg/kg showed significant improvement in MWM performance and learning memory deficit. Scopolamine also enhanced brain acetylcholinesterase activity, MDA level and decreased in GSH level. Sargassum wightii extract reversed the change in AChE activity, brain oxidative stress and histopathological changes in a significant level. The conclusion of this study suggested that the neuroprotective activity of Sargassum wightii against scopolamine-induced dementia like symptom probably through enhancement of cholinergic activity and reduced oxidative stress action.

Keywords: Neurodegenerative; Scopolamine; Sargassum wightii; Morris water maze; Acetylcholinesterase

Abstract
Simple, accurate, fast, and economical method for removal of OTC in Pharma wastewater has been developed. The procedure is based on the adsorption mechanism which leads to the spectrophotometry. Bentone -34 clay is used as an adsorbent for removal of OTC. 0.1 N HCl was used as a mobile phase. The elute was determined spectroscopically, with a Cecil CE 2041 UV/VIS spectrophotometer, in a 1-cm Cuvette cell at wavelength range 190-1100 nm, with resolution 0.5 nm. The linear calibration curve was established in the concentration range 0.214-1.070 mg/mL of OTC. From the analyzed data the following results for parameters were obtained linearity correlation R2> 0.9984), accuracy 
(Recovery = 91-98%), sensitivity (LOD = 42.3 mg/mL; LOQ = 48.3 mg/mL), and precision (RSD ≥ 2.0%) in the respective linear concentration ranges. The method is successfully applied for the removal of OTC as the tested sample improves ICH parameters like accuracy, sensitivity, precision.

Abstract
A total of one hundred and eighty (180) day old broiler chicks were used to evaluate the effect of blood vegetable waste meal with or without grit supplementation on the performance of broilers. The diets formulated had three inclusion levels of BVWM at 0, 7.5, and 15%, fed with two supplementation levels (with or without grit). The experimental animals were randomly distributed into six (6) dietary treatments. There were three replicates per treatment and ten (10) birds per replicate. Feed and water were provided ad-libitum while standard poultry managements were strictly followed during the study. Data on different performance such as average daily fee intake, average daily weight gain and feed conversion ratio. It was a 3X2 factorial experiment in a Completely Randomized Design (CRD). The experiment lasted for a period of 8 weeks. The result showed that the experimental diet had significant effect on the final weight gain, daily feed intake, weight gain, feed conversion ratio, cost of feed per kg and profitability. The interaction between the varying level of supplementation and no supplementation had significant effect (P<0.05) on feed to gain ratio, but showed no significant difference in final weight, daily feed intake. This study shows that broilers fed 15% inclusion level of blood vegetable waste meal supplemented with grit at 5% had better performance when compared to 0% and 5% inclusion.